Design of an Osteoinductive Extracellular Fibronectin Matrix Protein for Bone Tissue Engineering
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چکیده
منابع مشابه
Design of an Osteoinductive Extracellular Fibronectin Matrix Protein for Bone Tissue Engineering
Integrin-mediated cell-matrix interactions play an important role in osteogenesis. Here, we constructed a novel osteoinductive fibronectin matrix protein (oFN) for bone tissue engineering, designed to combine the integrin-binding modules from fibronectin (iFN) and a strong osteoinductive growth factor, bone morphogenetic protein-2. Compared with iFN, the purified oFN matrix protein caused a sig...
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The role of heart disease in increasing worldwide death and the limited availability of organs for transplantation have encouraged multiple strategies to fabricate functional and implantable constructs. One of these strategies is to develop a biologically similar heart tissue scaffold, in which two types of fiber and hydrogel are commonly used. Toward this goal, taking advantage of both hydroge...
متن کاملReinforcement of a decellularized extracellular matrix-derived hydrogel using nanofibers for cardiac tissue engineering
The role of heart disease in increasing worldwide death and the limited availability of organs for transplantation have encouraged multiple strategies to fabricate functional and implantable constructs. One of these strategies is to develop a biologically similar heart tissue scaffold, in which two types of fiber and hydrogel are commonly used. Toward this goal, taking advantage of both hydroge...
متن کاملThe Osteoinductive Property of Decalcified Bone Matrix an Experimental Study
Demineralised homologous bone-matrix implant was used to bridge a large circumferential osteoperiosteal gap in the diaphysis of the ulna of rabbits. Periodic observations of the graft were made clinically, radiologically, histologically and by tetracycline fluorescence up to forty-two weeks. By the twelfth week after operation 81 per cent of the animals revealed bone formation in the implant an...
متن کاملExtracellular Matrix Revisited: Roles in Tissue Engineering
[This corrects the article on p. S23 in vol. 20, PMID: 27230457.].
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2015
ISSN: 1422-0067
DOI: 10.3390/ijms16047672